Apoptosome refers to the adaptor protein complex that mediates the activation of an initiator caspase at the onset of apoptosis. In mammalian cells, caspase-9, caspase-8, and caspase-2 rely on the ...

Platelets are small anucleated blood cells responsible for stopping bleeding. They detect blood vessel damage and agglutinate, creating aggregates and stopping blood loss. This process is called ...

Targeting Signal Transducer and Activator of Transcription Signaling Pathway in Leukemias Drug development in cancer research is lengthy and expensive. One of the rate-limiting steps is the initiation ...