Creative Biolabs, a global leader in antibody engineering, today announced its optimization of ADCC and Fc-mediated ...

The ability to modulate high-mannose glycans during the production and reformulation of monoclonal antibodies (mAbs), antibody-drug conjugates, and biosimilars is an important factor affecting ...

Japanese researchers investigated how polyamines affect the functional profile of monoclonal antibodies and their production from CHO cells, and found that spermidine supplementation contributes to ...

Scientists from Croatia have identified 90 genes associated with the glycosylation of immunoglobulin (IgG). The team, who has already shown that 20 of these genes can be used to tweak glycosylation ...

(A) Structural propagation pathways originating from galactose residues within the Fc-linked glycan. (B) Galactose residues (indicated by yellow circles) suppress glycan mobility by acting as ...

Panelists discuss how immunoglobulin A (IgA) nephropathy develops through a complex 4-hit cascade involving aberrant IgA1 glycosylation, anti-glycan antibody formation, immune complex deposition, and ...

A Cornell-led collaboration has devised a potentially low-cost method for producing antibodies for therapeutic treatments. They've bioengineered bacteria with an overlooked enzyme that can attach ...

A unique glycosylation signature on circulating antibodies is detectable in blood up to 6 years before a diagnosis of Crohn's disease and could serve as a biomarker of future development and a target ...