The Warburg effect describes a shift from mitochondrial oxidative respiration to aerobic glycolysis that is commonly seen in cancer cells. A new study shows that the Warburg effect may combine with ...

推荐 为解决butyrate与anti-PD-1联合治疗CRC疗效不佳的问题，研究人员通过小鼠模型和细胞实验证实butyrate通过上调CPT1A促进脂肪酸氧化（FAO），削弱CD8+T细胞毒性，导致治疗抵抗。敲低CPT1A可恢复anti-PD-1疗效，提示靶向CPT1A可能增强免疫治疗效果。 论文解读 结直肠癌 ...

本研究针对过敏性哮喘治疗中糖皮质激素副作用大、生物制剂成本高等临床挑战，创新性地揭示了肠道菌群代谢物丁酸（butyrate）通过GPR43/p38 MAPK/NF-κB信号轴特异性抑制致病性Tfh13细胞，从而阻断高亲和力IgE产生的分子机制。研究人员开发了丁酸缓释淀粉（HAMSB ...

POSTECH and ImmunoBiome researchers uncover a novel microbiota-Tfh cell axis to enhance antibody production and mucosal ...

A six-week study from the University of Nottingham suggests that pairing fermented kefir with a diverse prebiotic fiber mix may deliver a powerful anti-inflammatory boost. This “synbiotic” combination ...

Supplementation with oral butyrate may be effective as a treatment for pediatric obesity, data indicate. In a randomized, placebo-controlled Italian study of more than 50 children with obesity, 6 ...

In the changed post COVID-19 business landscape, the global market for Sodium Butyrate estimated at US$217.6 Million in the year 2022, is projected to reach a revised size of US$477.6 Million by 2030, ...

Butyrate, a kind of short-chain fatty acid, is produced in the colon via the fermentation of dietary fiber. This crucial compound significantly contributes to maintaining gut health and is linked to ...

Your gut's petrol maybe running low and it is causing you all sorts of gut issues. But, what does it really mean? Bloating that doesn’t settle, gas that feels unpredictable, sluggish digestion, and a ...