DENVER, Jan. 28, 2026 (GLOBE NEWSWIRE) -- CRISPR gene-editing, and related genome engineering technologies, are reshaping industries from medicine to materials, with breakthroughs in treating genetic ...
L-selectin检测新型荧光生物传感器研发:采用分裂aptamer与CRISPR-Cas12a联用及3D-DNA漫步技术,实现0.45 ng/mL超灵敏检测,线性范围10-1280 ng/mL,有效应用于人体血液样本的定量分析,为炎症和免疫相关疾病提供高精度诊断工具。 L-选择素是一种白细胞粘附受体,在粘附 ...
近日,北京大学化学与分子工程学院本科校友、美国威斯康星麦迪逊大学博士毕业生、目前正在斯坦福大学从事博士后研究的朱彦宇和所在团队研发出一种高时空分辨率的活细胞 DNA 成像技术 Oligo-LiveFISH。该技术基于 sgRNA 的序列特异性识别能力和定制化寡核苷酸 ...
本研究针对DNA损伤剂(DDA)与DNA损伤修复(DDR)通路间复杂的化学基因组互作网络尚未完全阐明的现状,开发了靶向353个DDR基因的CRISPR敲除筛选平台。研究人员在LN229胶质瘤细胞中系统评估了15种DDA的修复依赖性,不仅验证了已知互作(如FA通路修复ICL、MMR缺失导致甲基 ...
Picture CRISPR-Cas9, a gene editing technology, as a GPS-guided scalpel: gRNA directs the Cas9 enzyme, a protein that cuts ...
Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields. Now scientists are applying the technology's immense potential to human ...
细菌与噬菌体之间的军备竞赛已经持续了数十亿年。这场没有硝烟的战争催生了地球上最复杂、最精巧的防御系统。当我们以为自己已经通过Cas9、Cas12a或Cas13窥探到了CRISPR-Cas系统的全貌时,自然界总能以一种令人惊叹的方式提醒我们:我们所知的,不过是冰山一角。
A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...
A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, ...
Researchers from Excision Biotherapeutics Inc. and affiliated organizations have reported the development of a novel CRISPR/Cas9-mediated genome editing therapy – EBT-104 – for the treatment of latent ...
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