Researchers at Tsinghua University have released a novel Python toolkit, scLT-kit, which automates the processing and analysis of single-cell lineage tracing data, delivering clear insights into how ...

The workflow of scLT-kit. Based on the time-series lineage tracing single-cell data (top left panel), scLT-kit calculates the barcoding fraction and clone sizes (top right panel, scLT-statistics ...

Cancer cells don’t just shape shift. They state shift. That is, they can embody different cell states, or types, that possess different degrees of plasticity or hereditability. If cancer cells become ...