Septins are a conserved family of GTP-binding proteins that assemble into filamentous structures, earning them recognition as the fourth component of the cytoskeleton alongside actin, microtubules and ...

Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death. As the cellular reactions to a cerebral infarction are not yet fully understood, there is ...

Researchers at UC Merced used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging. Department of Molecular and Cell ...

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...