Nuclear pore complexes (NPCs) govern macromolecular transport between the nucleus and cytoplasm and serve as key positional markers within the nucleus. Several protein components of yeast NPCs have ...

Classical dendritic cells (cDCs) are essential for immune responses and differentiate from hematopoietic stem cells via intermediate progenitors, such as monocyte–DC progenitors (MDPs) and common DC ...

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.

Our understanding of complex genomes has benefited tremendously from whole genome sequencing projects. However, we are only beginning to systematically understand how the interplay of DNA, proteins ...

Basic biology textbooks may need a bit of revising now that biologists have discovered a never-before-noticed component of our basic genetic material. Basic biology textbooks may need a bit of ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...