The new program is validated in a set of clinical pedigrees demonstrating its practical accuracy and relevance to the field. Collectively, the data are compelling and support the major conclusions of ...

Understanding the network organization of the brain has been a long-standing challenge for neuroscience. In the past decade, developments in graph theory have provided many new methods for ...

We have determined the structure, at 2.6 Å resolution, of the AML1 (Runx1) Runt domain–CBFβ–DNA ternary complex, the most common target for mutations in human leukemia. The structure reveals that the ...

The exocyst, an octameric tethering complex and effector of Rho and Rab GTPases, facilitates polarized secretion in yeast and animals. Recent evidence implicates three plant homologs of exocyst ...

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image ...

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and ...