While industrial bioprocesses have been operated in fed-batch mode for a long time, the screening of high-producer cell lines and a lot of other development work is still performed in batch mode for a ...

The Rocky Mountain Journal of Mathematics, Vol. 38, No. 5, Special Issue: Proceedings of the 4th International Conference on Mathematical Biology (2008), pp. 1377-1384 (8 pages) In this study, the ...

A conventional production fed-batch process involves a multi-stage seed expansion and elaborate clarification steps to isolate the protein of interest from other process impurities. The current ...