A patent foramen ovale (PFO) is a hole in the heart that doesn’t close as expected after birth. Before a baby is born, they have a hole between the left and right sides of their heart. This hole, ...

Patent foramen ovale (PFO) has been linked to ischemic strokes of undetermined cause (cryptogenic strokes). PFO—a remnant of fetal circulation when the foramen ovale does not seal after birth—can ...

A 46-year-old female with no previously documented illnesses presented with 15 months of diarrhea, abdominal pain, and flushing after alcohol consumption. Abdominal CT showed multiple hepatic masses, ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Studies to date have shown an association between the presence of patent foramen ovale and cryptogenic stroke in patients younger than 55 years of age. This association has not been established in ...

† New-onset migraine was noted in ten patients. ASD: Atrial septal defect; NA: Not assessed; NR: Not reported; PFO: Patent foramen ovale. The following arguments support the hypothesis that ...

This section describes efficacy outcomes from the published literature that the Committee considered as part of the evidence about this procedure. For more detailed information on the evidence, see ...

A patent foramen ovale is an opening that some adults have between the top two chambers of their hearts. Everyone has this opening early in life, but it often seals during infancy. In some people, ...

This section describes efficacy outcomes from the published literature that the Committee considered as part of the evidence about this procedure. For more detailed information on the evidence, see ...

Please provide your email address to receive an email when new articles are posted on . The persistently patent foramen ovale has been implicated in a variety of neurologic and embolic events, ...

Please provide your email address to receive an email when new articles are posted on . Abbott announced that the FDA has approved its patent foramen ovale occlusion system for patients with a PFO and ...

Though its often harmless, the condition called PFO can be life-threatening. Learn about patent foramen ovale.