免疫检查点抑制剂（ICIs）联合化疗已成为多种晚期恶性肿瘤的标准一线治疗方案，能带来显著的生存获益，但化疗的骨髓抑制风险却像悬在头顶的“达摩克利斯之剑”——一旦发生严重的中性粒细胞减少或FN，不仅可能导致治疗中断，还可能引发危及生命的感染。这时，粒细胞集落刺激因子（G-CSF）作为一种经典的升白细胞药物就像一张精心编织的“安全网”。但在免疫治疗联合化疗的“强强组合”中，G-CSF的使用是否会“帮倒 ...

2026年2月12日星期四，X4制药公司 (NASDAQ:XFOR)在2026年古根海姆证券新兴展望：生物技术峰会上展示了其战略前景。执行主席Adam Craig概述了公司在开发mavorixafor治疗慢性中性粒细胞减少症方面的重点，强调了运营效率和战略优先级。公司旨在精简运营，同时应对商业化和定价策略方面的挑战。

Efficacy comparison of anthracycline and taxane when added to immune checkpoint inhibitor in neoadjuvant chemotherapy of triple negative breast cancer: Clinical evidence from size-reduction ...

Neonatal alloimmune neutropenia is due to maternal production of antibodies directed against neutrophil specific antigens (NA1, NA2, NB1, NC1) reacting with fetal-neonatal and paternal neutrophils.

When the use of prophylactic granulocyte-colony stimulating factor (G-CSF) to reduce febrile neutropenia (FN) was decreased in patients receiving chemotherapy for breast cancer, it led to a more than ...

In response to a high oxygen insult, the lungs of wild-type mice (left-hand side) show alveolar simplification and enlargement, septal wall thickening (blue arrow), and leukocyte infiltration (black ...

Erratum: ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma Treatment Intensification With Either ...

Spectrum Pharmaceuticals Inc. celebrated a long-awaited win with the U.S. FDA’s approval late Sept. 9 of novel G-CSF drug eflapegrastim, cleared for use in chemotherapy-induced neutropenia nearly four ...

WASHINGTON -- Research presented here at the annual Liver Meeting sponsored by the American Association for the Study of Liver Diseases included a better combination for severe alcoholic hepatitis, ...

A study published in the Journal of Cannabis Research examined the effect of granulocyte colony-stimulating factor (G-CSF) on brain recovery following traumatic brain injury (TBI). The findings showed ...