The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Researchers have shown for the first time that flipping an epigenetic “switch” in specific memory-holding neurons can directly alter memory strength.

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

Engineers have created DIAL, a modular system that precisely sets and edits protein levels in synthetic gene circuits. By altering spacer DNA between promoters and genes, researchers can control ...

Our experiences leave traces in the brain, stored in small groups of cells called engrams. Engrams are thought to hold the ...