AlphaGenome 能够一次性分析多达 100 万个 DNA 碱基对，预测突变如何干扰基因的调控方式，如何改变其激活时机、在体内哪些细胞中表达，以及其生物调控开关是处于高或低的状态。来源 Nature来源 卫报翻译 科研圈bot1 月 28 ...

Although it is an important technology for studying genomes, DNA sequencing was initially accomplished in 1977 by Frederick Sanger. Since its conception, the technology has developed rapidly. Alvaro G ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

The first resource containing high-resolution DNA sequencing data for over 37,000 children and parents collected over multiple decades from across the UK is now available to researchers worldwide. The ...

Powered by GeneDx Infinity™ with unparalleled scale and diversity, GeneDx fuels breakthrough scientific research and delivers the most precise rare disease diagnosis for patients and families “GeneDx ...

The Next Generation Sequencing (NGS) field has been in constant flux since a wave of newcomers entered the field several years ago that changed the game. The startups offered sequencing users new ...

Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Scientists have uncovered an unexpected genetic shift that may explain how animals with backbones first emerged and became so diverse.