Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...

Tautz et al. (2026): Beyond Mendel: a call to revisit the genotype–phenotype map through new experimental paradigms, Genetics Vol. 232, doi: https://doi.org/10.1093/genetics/iyag024 ...

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen ...

Between 1856 and 1863, an Austrian monk named Gregor Mendel performed a series of pioneering experiments by breeding plants. Using garden peas (Pisum sativum), he demonstrated that traits such as seed ...

The Y chromosome is inherited only through the paternal line. Sons receive their Y chromosome exclusively from their father.

How much of our lifespan is written in our genes, and how much is sitting on our plates? A new analysis suggests that while ...

IN 1865, an Austrian monk called Gregor Mendel, working to understand hybridisation, uncovered exquisitely simple and reliable patterns of inheritance in varieties of garden pea. In 1900, the patterns ...

Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...