Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

This study focused on how NMDAR, an important cell surface receptor, triggers a complex chemical cascade in postsynaptic neurons in the nucleus accumbens region of the brain. More specifically, the ...

Scientists discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis. A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching effects regarding immune responses, inflammatory processes, and diseases. A ...