The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

IPA, a non-coding RNA from the CUL1 gene that stabilizes the nucleolus and supports ribosome production. Removing it ...

In a recent study, researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism that cell belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...

At most, 10 people in the world are known to have BPTA. Five of them participated in the current study, and they were found to share virtually the same mutation in the gene for the HMGB1 protein. It ...

Sang Hyon Kim, Olga A. Koroleva, Dominika Lewandowska, Ali F. Pendle, Gillian P. Clark, Craig G. Simpson, Peter J. Shaw and John W. S. Brown The eukaryotic nucleolus is multifunctional and involved in ...