Amplicon vectors 1 are HSV-1 particles identical to wild-type HSV-1 from the structural, immunological and host-range points of view, but which carry a concatemeric form of a DNA plasmid, named the ...

We have previously described a defective herpes simplex virus (HSV-1) vector system that permits the introduction of virtually any gene into nonmitotic cells. pHSVlac, the prototype vector, stably ...