Correspondence to Dr Lauren Pringels, Department of Physical and Rehabilitation Medicine, Ghent University Hospital, Ghent, Belgium; Lauren.Pringels{at}UGent.be Despite the high prevalence of tendon ...

A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

The research in Singh laboratory is broadly focused on the pathophysiology of iron in disorders of the brain and the eye. Current interests in the lab include: Iron cycling in the eye. Pathophysiology ...

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the ...

Like all forms of cancer, lung cancer is defined by uncontrolled cell division caused by loss of physiological tissue homeostasis and failure of apoptotic cell death mechanisms. Aberrant cell ...

Mitochondria are instrumental in maintaining human brain homeostasis, and disturbed mitochondria associate with neuronal dysfunction and related pathology in neurodegenerative diseases including ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap ...

The role of neuron and dopamine loss in Parkinson's Disease (PD) has long been recognized by neuroscientists. However, how dopaminergic modulation affects brain regions involved in the control of ...

What are the lasting effects of COVID-19 on the body? Paul Benson, M.D., Professor and Autopsy Section Head in the Department of Pathology's Division of Anatomic Pathology, was awarded a Researching ...