Skeletal muscle is pivotal not only for movement but also for systemic metabolic regulation. Its physiology encompasses intricate networks of contractile machinery, mitochondrial dynamics, and ...

This is a preview. Log in through your library . Abstract Stimuli are translated to intracellular calcium signals via opening of inositol trisphosphate receptor and ryanodine receptor (RyR) channels ...

VOL: 102, ISSUE: 48, PAGE NO: 26 Marion Richardson BD, RN, CertEd, DipNurs, RNT, is senior lecturer, University of Hertfordshire. Subscribe today for unlimited access to 6,000+ clinical articles, ...

Researchers have investigated the effect of increased cell temperature on the contractility of skeletal muscle and cardiac muscle by heating the muscle proteins using advanced microscopical techniques ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Bones and skeletal muscles undergo a gradual age-related degeneration that accelerates frailty and makes older people more prone to sarcopenia, osteoporosis, osteoarthritis and falls Abstract With ...

Cachexia affects the majority of patients with advanced cancer and is associated with a reduction in treatment tolerance, response to therapy, quality of life, and duration of survival. It is a ...