A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

Researchers in Japan have reported a solvent-free technique that uses heat and vacuum to convert poorly soluble drugs into more bioavailable amorphous forms, addressing a central bottleneck in ...

These plots show powder X-ray diffraction measurements of three different types of formulations: simple mixing (a, d), the conventional evaporation/condensation ...

A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

Poor drug solubility has become a challenge for pharmaceutical companies, with an approximation of 40% of drugs in their developing stages demonstrating problems with drug solubility. Additionally, ...