Comparison of PREMM5 and PREMMplus Risk Assessment Models to Identify Lynch Syndrome Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house ...

Scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new ...

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints ...

Cancer is no longer seen as a single genetic error but as a complex, multi-layered disease shaped by DNA mutations, epigenetic changes and even patterns in medical images. New research at ...

The Cancer Gene Census (CGC) is a widely used module within the Catalogue Of Somatic Mutations In Cancer (COSMIC) that comprises an ongoing effort to catalogue and describe all genes with causal ...

JCO Precision Oncology Conversations features discussions with leading authors of JCO Precision Oncology articles, hosted by Dr. Abdul Rafeh Naqash. Join our experts in engaging conversations as they ...

Precision medicine in prostate cancer utilizes genetic testing to identify patients for PARP inhibitor treatment, enhancing personalized care. Genetic testing, including germline and somatic, is ...

Cancer cannot be explained by mutations alone. Today, cancer is understood as a multifactorial disease, shaped by genetics, ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...