The aminoacylation reaction, which is catalysed by aminoacyl-tRNA synthetases (aaRSs), fuses each amino acid to its cognate tRNA. This reaction requires amino acid activation through condensation of ...

Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...

The MYC gene is induced by a wealth of growth factors and is essential for most normal cells to proliferate 1,2. Following the deregulation of MYC expression by translocation, gene amplification or ...