Researchers identify altered expression of genes that worsens periodontitis among smokers, and a new target molecule ...

The clinical and immunological significance of granulomatous disease is underscored by its role as a hallmark and common manifestation of pulmonary infections caused by Mycobacterium tuberculosis (Mtb ...

Model vs Naive Baseline — Comparing model 2μm predictions against simply upsampling 8μm ground truth (4×4 nearest neighbor). The baseline wins on this gene.

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Abstract: Spatial transcriptomics technology enables researchers to acquire both spatial location information and gene expression data within tissues, providing new perspectives for understanding ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

I would like to use UCell to score a gene signature across a 10x Genomics Visium spatial transcriptomics dataset. It is also in an SFE object which inherits all functions that are used with SCE so ...

Background: Dysregulated fibroblasts and macrophages have been implicated in vascular remodeling in pulmonary arterial hypertension (PAH). Macrophages are known to modulate fibroblast activity in ...

Background: Lung tissue exhibits intricate spatial organization and dynamic cellular interactions. However, the molecular mechanisms underlying pulmonary arterial hypertension (PAH) remain poorly ...