Mechanism of NMDA Receptor Inhibition and Activation.
vanderbilt.edu
Mechanism of NMDA Receptor Inhibition and Activation.
N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated, calcium-permeable ion channels that mediate synaptic transmission and underpin learning and memory. NMDAR dysfunction is directly implicated in diseases ranging from seizure to ischemia. Despite its fundamental importance, little is known about how the NMDAR transitions between ...
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